Lopez Vazquez was born in Madrid. During his life, he starred in more than 200 movies, filming several full-length films in a year. In 1971, he acted in a record 11 films.
Although he usually appeared in Spanish films, he has occasionally worked on international projects: in the UK film "Travels With My Aunt" from 1972, starring opposite Dame Maggie Smith. His best known role may be in the Emmy-winning film, "La Cabina", which was made the same year with director Antonio Mercero. Lopez Vazquez worked with Mercero on numerous other occasions, the most recent being their collaboration on a new project, a movie called "Y tu quien eres?" (2006).